I enjoyed reading this, and felt very quickly that I was 'inside' the head of the MC, and I was completely engaged.
Although this is seemingly not going to a plot-driven story, I did notice that nothing seems to really happen in this opening chapter: it's predominantly introspection and flashbacks. This type of content, although definitely interesting and absorbing, is 'slow'... so by the end of it, I didn't feel like I had properly started the story itself yet, and I wanted to.
In answer to your questions specifically:
1. Yes I felt it was successfully 'grounded' now (although I haven't read the first draft yet, so can't comment specifically on the changes you've made). Your depiction of the main character drew me in and I felt able to empathise completely with her feelings and emotions, and visualise the scenes you describe in the flashback clearly.
2. Despite not being a plot-driven story as I just said, in my humble opinion it does still need to be a story first and foremost. It's from that that any 'self-help' component will come: your readers will identify and empathise with your MC, and take the necessary messages for themselves away from the book via that. Your goal can, by all means, be to craft a narrative that will offer wide-reaching and genuinely beneficial 'life lessons' to your readers; but my own feeling is that if you market it that way explicitly, it'll run the risk of sounding like you're trying to be a bit 'preachy': "Read this because it will show you how to fix yourself if you're suffering from depression". (Do you know what I mean?) So my thoughts on your Qu2 are that it might be better to be a bit discreet about the 'self help' part of the book's purpose, and let readers figure that part out for themselves.
Hope some of this helps :-)